| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CD105 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the CD105 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This CD105 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
2022 |
| Purity: |
Antigen affinity |
| Description: |
CD105 has a role in the development of the cardiovascular system and in vascular remodeling and has been found to be elevated in pregnant women who subsequently develop preeclampsia, It has been found on endothelial cells, Its gene is mapped to human chromosome 8, The protein consists of a homodimer of 180 kDA with disulfide links, activated macrophages, fibroblasts and smooth muscle cells, CD105 is a type I membrane glycoprotein located on cell surfaces and is a part of the TGF beta receptor complex |
| Immunogen: |
Human partial recombinant protein (AA 26-384) was used as the immunogen for this CD105 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CD105 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CD105 |
| Short name: |
CD105 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD105 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3349 |
| Gene: |
ENG |
More about : ENG |
| Long gene name: |
endoglin |
| Synonyms gene: |
ORW1 ORW |
| Synonyms gene name: |
Osler-Rendu-Weber syndrome 1 |
| Synonyms: |
END HHT1 CD105 |
| Locus: |
9q34, 11 |
| Discovery year: |
1993-03-03 |
| GenBank acession: |
AF035753 |
| Entrez gene record: |
2022 |
| Pubmed identfication: |
8404038 10548503 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000020723 |
| Locus Specific Databases: |
Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database LRG_589 |