| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CD105 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the CD105 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CD105 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P17813 |
| Purity: |
Purified |
| Description: |
Mutations in its gene cause hereditary hemorrhagic telangiectasia, This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia, CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium |
| Immunogen: |
A portion of amino acids 380-409 from the human protein was used as the immunogen for this CD105 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD105 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CD105 |
| Short name: |
CD105 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD105 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3349 |
| Gene: |
ENG |
More about : ENG |
| Long gene name: |
endoglin |
| Synonyms gene: |
ORW1 ORW |
| Synonyms gene name: |
Osler-Rendu-Weber syndrome 1 |
| Synonyms: |
END HHT1 CD105 |
| Locus: |
9q34, 11 |
| Discovery year: |
1993-03-03 |
| GenBank acession: |
AF035753 |
| Entrez gene record: |
2022 |
| Pubmed identfication: |
8404038 10548503 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000020723 |
| Locus Specific Databases: |
Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database LRG_589 |