| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AKT2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the AKT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This AKT2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
208 |
| Purity: |
Antigen affinity |
| Description: |
-2 and -3) called the AKT kinase, AKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 seems also to be the principal isoform responsible of the regulation of glucose uptake, It is also specifically involved in skeletal muscle differentiation, Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers, This gene is mapped to 19q13, and which regulate many processes including metabolism, cell survival, growth and angiogenesis, one of its substrates in this process being ANKRD2, proliferation, 2, AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains |
| Immunogen: |
An amino acid sequence from the C-terminus of human AKT2 (DRYDSLGLLELDQRTHFPQFSYSASIRE) was used as the immunogen for this AKT2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the AKT2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AKT2 |
| Short name: |
AKT2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
v-akt murine thymoma viral oncogene homolog 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AKT2 and IDBG-51270 and ENSG00000105221 and 208, AKT2 and IDBG-637808 and ENSBTAG00000001400 and 534923, Akt2 and IDBG-161456 and ENSMUSG00000004056 and 11652, HIHGHH and PKBB and PKBBETA and PRKBB and RAC-BETA, nuclei, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0005978 and glycogen biosynthetic process and biological process this GO :0006006 and glucose metabolic process and biological process this GO :0006417 and regulation of translation and biological process this GO :0006464 and cellular protein modification process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008643 and carbohydrate transport and biological process this GO :0010748 and negative regulation of plasma membrane long-chain fatty acid transport and biological process this GO :0010907 and positive regulation of glucose metabolic process and biological process this GO :0016301 and kinase activity and molecular function this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0030334 and regulation of cell migration and biological process this GO :0031340 and positive regulation of vesicle fusion and biological process this GO :0032000 and positive regulation of fatty acid beta-oxidation and biological process this GO :0032287 and peripheral nervous system myelin maintenance and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032859 and activation of Ral GTPase activity and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0061024 and membrane organization and biological process this GO :0065002 and intracellular protein transmembrane transport and biological process this GO :0071156 and regulation of cell cycle arrest and biological process this GO :0072659 and protein localization to plasma membrane and biological process this GO :0090314 and positive regulation of protein targeting to membrane and biological process this GO :2000147 and positive regulation of cell motility and biological process this GO :2001275 and positive regulation of glucose import in response to insulin stimulus and biological process, v-akt murine thymoma viral oncogene homolog 2 |
| Identity: |
392 |
| Gene: |
AKT2 |
More about : AKT2 |
| Long gene name: |
AKT serine/threonine kinase 2 |
| Synonyms gene name: |
v-akt murine thymoma viral oncogene homolog 2 |
| Locus: |
19q13, 2 |
| Discovery year: |
1992-11-05 |
| GenBank acession: |
M77198 |
| Entrez gene record: |
208 |
| Pubmed identfication: |
1409633 |
| RefSeq identity: |
NM_001626 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000137375 |