| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CCL7 (MCP3) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, ELISA: 0, Western blot: 0 |
| Notes: |
Titration of the CCL7 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This CCL7 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
20306 |
| Purity: |
Antigen affinity |
| Description: |
-2, By fluorescence in situ hybridization, Cleaved MCP3/CCL7 binds to CC-chemokine receptors-1, It belongs to the C-C chemokine family, MCP3 was identified as a physiologic substrate of gelatinase A, and -3, and instead acts as a general chemokine antagonist that dampens inflammation, but no longer induces calcium fluxes or promotes chemotaxis, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response, the gene is mapped to chromosome 17q11, 2-q12, Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3) |
| Immunogen: |
Mouse partial recombinant protein (AA 24-97) was used as the immunogen for this CCL7 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CCL7 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CCL7 (MCP3) |
| Short name: |
CCL7 Antibody (MCP3) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-C motif) ligand 7 (Antibody to) (MCP3) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CCL7 and IDBG-40580 and ENSG00000108688 and 6354, CCR2 chemokine receptor binding, Ccl7 and IDBG-204496 and ENSMUSG00000035373 and 20306, Extracellular, FIC and MARC and MCP-3 and MCP3 and NC28 and SCYA6 and SCYA7, this GO :0002548 and monocyte chemotaxis and biological process this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0008360 and regulation of cell shape and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031726 and CCR1 chemokine receptor binding and molecular function this GO :0031727 and CCR2 chemokine receptor binding and molecular function this GO :0048245 and eosinophil chemotaxis and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0071361 and cellular response to ethanol and biological process this GO :2000503 and positive regulation of natural killer cell chemotaxis and biological process, this GO :0008009 : chemokine activity, this GO :0008009 : chemokine activity and also this GO :0008201 : heparin binding and also this GO :0031726 : CCR1 chemokine receptor binding and also this GO :0031727 : CCR2 chemokine receptor binding, this GO :0008201 : heparin binding, this GO :0031726 : CCR1 chemokine receptor binding, this GO :0031727 : CCR2 chemokine receptor binding, chemokine (C-C motif) ligand 7 |
| Identity: |
10634 |
| Gene: |
CCL7 |
More about : CCL7 |
| Long gene name: |
C-C motif chemokine ligand 7 |
| Synonyms gene: |
SCYA6 SCYA7 |
| Synonyms gene name: |
small inducible cytokine A7 (monocyte chemotactic protein 3) chemokine (C-C motif) ligand 7 |
| Synonyms: |
MCP-3 NC28 FIC MARC MCP3 |
| Synonyms name: |
monocyte chemoattractant protein 3 monocyte chemotactic protein 3 |
| Locus: |
17q12 |
| Discovery year: |
1993-11-04 |
| GenBank acession: |
AF043338 |
| Entrez gene record: |
6354 |
| Pubmed identfication: |
8461011 |
| RefSeq identity: |
NM_006273 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000132889 |