| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IL1 beta |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Rat |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, ELISA: 0, Western blot: 0 |
| Notes: |
Titration of the IL1 beta antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This IL1 beta antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
24494 |
| Purity: |
Antigen affinity |
| Description: |
Additional, Furthermore, IL-1alpha are required for in vivo angiogenesis and invasiveness of different tumor cells, IL-1beta, It also can cause nuclear export of a specific NCOR corepressor complex, Microenvironmental IL-1beta and, Moreover, a prominent microglia-derived cytokine, and has been implicated in the pathogenesis of high bone turnover and osteoporosis, but not in pure culture of oligodendrocytes alone, caused oligodendrocyte death in coculture with astrocytes and microglia, resulting in derepression of a specific subset of nuclear factor-kappa-B (NFKB)-regulated genes, the association with disease may be explained by the biologic properties of IL-1beta, the cooperation of IL-1beta and PDGFB induces contractile-to-synthetic phenotype modulation of human aortic smooth muscle cells in culture, to a lesser extent, which is an important proinflammatory cytokine and a powerful inhibitor of gastric acid secretion, Interleukin-1beta (IL-1beta) is a potent stimulator of bone resorption whose gene is mapped to 2q14 |
| Immunogen: |
Rat partial recombinant protein (AA 117-268) was used as the immunogen for this IL1 beta antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IL1 beta antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IL1 beta |
| Short name: |
IL1 beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
IL1 b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5991 |
| Gene: |
IL1A |
More about : IL1A |
| Long gene name: |
interleukin 1 alpha |
| Synonyms gene: |
IL1 |
| Synonyms: |
IL1F1 IL-1A IL1-ALPHA |
| Synonyms name: |
preinterleukin 1 alpha hematopoietin-1 pro-interleukin-1-alpha |
| Locus: |
2q14, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M28983 |
| Entrez gene record: |
3552 |
| Pubmed identfication: |
8188271 2989698 |
| RefSeq identity: |
NM_000575 |
| Classification: |
Endogenous ligands Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000131315 |