| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PBK |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the PBK antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This PBK antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q96KB5 |
| Purity: |
Antigen affinity |
| Description: |
Evidence suggests that mitotic phosphorylation is required for its catalytic activity, It is mapped to 8p21, Overexpression of this gene has been implicated in tumorigenesis, PBK can mediate cell growth through histone H3 modification, The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, The protein encoded by this gene is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family, also known as TOPK or PBK (PDZ binding kinase, is an enzyme that in humans is encoded by the PBK gene, with a suggested role in the process of spermatogenesis, ), 1, Lymphokine-activated killer T-cell-originated protein kinase |
| Immunogen: |
An amino acid sequence from the C-terminus of human PDZ binding kinase (KDRPSAAHIVEALETDV) was used as the immunogen for this PBK antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PBK antibody can be stored for up to one month at 4oC, After reconstitution |
| Localization: |
Nuclear and cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PBK |
| Short name: |
PBK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PBK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18282 |
| Gene: |
PBK |
More about : PBK |
| Long gene name: |
PDZ binding kinase |
| Synonyms: |
TOPK FLJ14385 Nori-3 SPK CT84 |
| Synonyms name: |
T-LAK cell-originated protein kinase cancer/testis antigen 84 |
| Locus: |
8p21, 1 |
| Discovery year: |
2005-01-20 |
| GenBank acession: |
AB027249 |
| Entrez gene record: |
55872 |
| Pubmed identfication: |
10781613 10779557 |
| RefSeq identity: |
NM_018492 |
| Havana BLAST/BLAT: |
OTTHUMG00000102113 |