| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NGFR Nerve Growth Factor Receptor |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the NGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This NGFR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P08138 |
| Purity: |
Antigen affinity |
| Description: |
FSCN1, It has been shown to interact with PRKACB, It is mapped to 17q21, NDN, NGFR is a receptor for rabies virus, NGFR is involved in activity-dependent synaptic plasticity, NGFRAP1 and MAGEH1, Nerve growth factor, Overexpression of the protein was also found to activate the SM pathway, TRAF2, TRAF4, This gene is a signaling partner for EPHAs and the EPHA/NGFR complex reverse signals can mediate axon repulsion required for guidance and mapping, a family of protein growth factors that stimulate neuronal cells to survive and differentiate, and it is also a coreceptor for the NOGO receptor for MAG signaling, 33, The Low-Affinity Nerve Growth Factor Receptor(also called the NGFR or p75 neurotrophin receptor) is one of the two receptor types for the neurotrophins |
| Immunogen: |
An amino acid sequence from the C-terminus of human Nerve growth factor receptor (TLDALLAALRRIQRADLV) was used as the immunogen for this NGFR antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the NGFR antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NGFR Nerve Growth Factor Receptor |
| Short name: |
NGFR Antibody Nerve Growth Factor Receptor |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
nerve growth factor receptor (Antibody to) Nerve Growth Factor Receptor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD271 and Gp80-LNGFR and p75(NTR) and p75NTR and TNFRSF16, NGFR and IDBG-57653 and ENSG00000064300 and 4804, NGFR and IDBG-638806 and ENSBTAG00000020979 and 353110, Ngfr and IDBG-209608 and ENSMUSG00000000120 and 18053, nerve growth factor binding, nuclei, this GO :0004871 and signal transducer activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005035 and death receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006886 and intracellular protein transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0007417 and central nervous system development and biological process this GO :0009986 and cell surface and cellular component this GO :0010468 and regulation of gene expression and biological process this GO :0012501 and programmed cell death and biological process this GO :0016048 and detection of temperature stimulus and biological process this GO :0017137 and Rab GTPase binding and molecular function this GO :0021675 and nerve development and biological process this GO :0031069 and hair follicle morphogenesis and biological process this GO :0031293 and membrane protein intracellular domain proteolysis and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032922 and circadian regulation of gene expression and biological process this GO :0040037 and negative regulation of fibroblast growth factor receptor signaling pathway and biological process this GO :0042488 and positive regulation of odontogenesis of dentin-containing tooth and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043588 and skin development and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048406 and nerve growth factor binding and molecular function this GO :0050770 and regulation of axonogenesis and biological process this GO :0050771 and negative regulation of axonogenesis and biological process this GO :0050772 and positive regulation of axonogenesis and biological process this GO :0051799 and negative regulation of hair follicle development and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097481 and neuronal postsynaptic density and cellular component this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process this GO :2001273 and regulation of glucose import in response to insulin stimulus and biological process, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0004872 : receptor activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005035 : death receptor activity and also this GO :0005515 : protein binding and also this GO :0017137 : Rab GTPase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0048406 : nerve growth factor binding, this GO :0004872 : receptor activity, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005035 : death receptor activity, this GO :0005515 : protein binding, this GO :0017137 : Rab GTPase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0048406 : nerve growth factor binding, nerve growth factor receptor |
| Identity: |
7809 |
| Gene: |
NGFR |
More about : NGFR |
| Long gene name: |
nerve growth factor receptor |
| Synonyms gene name: |
member 16) , nerve growth factor receptor (TNFR superfamily |
| Synonyms: |
TNFRSF16 CD271 p75NTR |
| Synonyms name: |
low affinity nerve growth factor receptor TNFR superfamily, member 16 |
| Locus: |
17q21, 33 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M14764 |
| Entrez gene record: |
4804 |
| Pubmed identfication: |
3022937 3006050 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000161495 |