| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CADM1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the CADM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This CADM1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9BY67 |
| Purity: |
Antigen affinity |
| Description: |
Conversely, Expression of the isolated cytoplasmic tail of CADM1 in neurons inhibited synapse assembly, It functions as a homophilic cell adhesion molecule at the synapse, It has been shown to interact with EPB41L3, SYNCAM or TSLC1, This gene is also known as IGSF4, and it is mapped to 11q23, expression of full-length protein in non-neuronal cells induced synapse formation by cocultured hippocampal neurons with normal release properties, in humans, is encoded by the CADM1 gene, 3, Cell adhesion molecule 1 is a protein that |
| Immunogen: |
mouse and rat), An amino acid sequence from the N-terminus of human SynCAM/CADM1 (VIQLLNPNRQTIYFRDFRPL) was used as the immunogen for this CADM1 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CADM1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CADM1 |
| Short name: |
CADM1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
cellular adhesion molecule 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BL2 and IGSF4 and IGSF4A and Necl-2 and NECL2 and RA175 and sgIGSF and ST17 and sTSLC-1 and SYNCAM and synCAM1 and TSLC1, CADM1 and IDBG-630721 and ENSBTAG00000000977 and 529873, CADM1 and IDBG-72227 and ENSG00000182985 and 23705, Cadm1 and IDBG-161668 and ENSMUSG00000032076 and 54725, Cell surfaces, cell adhesion molecule binding, this GO :0001889 and liver development and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007416 and synapse assembly and biological process this GO :0007420 and brain development and biological process this GO :0008021 and synaptic vesicle and cellular component this GO :0008022 and protein C-terminus binding and molecular function this GO :0008037 and cell recognition and biological process this GO :0009826 and unidimensional cell growth and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016338 and calcium-independent cell-cell adhesion and biological process this GO :0030154 and cell differentiation and biological process this GO :0030165 and PDZ domain binding and molecular function this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0042271 and susceptibility to natural killer cell mediated cytotoxicity and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043005 and neuron projection and cellular component this GO :0045202 and synapse and cellular component this GO :0045216 and cell-cell junction organization and biological process this GO :0045954 and positive regulation of natural killer cell mediated cytotoxicity and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0051606 and detection of stimulus and biological process this GO :0060348 and bone development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0008022 : protein C-terminus binding and also this GO :0030165 : PDZ domain binding and also this GO :0042803 : protein homodimerization activity and also this GO :0050839 : cell adhesion molecule binding, this GO :0005515 : protein binding, this GO :0008022 : protein C-terminus binding, this GO :0030165 : PDZ domain binding, this GO :0042803 : protein homodimerization activity, this GO :0050839 : cell adhesion molecule binding, cell adhesion molecule 1 |
| Identity: |
5951 |
| Gene: |
CADM1 |
More about : CADM1 |
| Long gene name: |
cell adhesion molecule 1 |
| Synonyms gene: |
TSLC1 IGSF4 |
| Synonyms gene name: |
member 4 , tumor suppressor in lung cancer 1 immunoglobulin superfamily |
| Synonyms: |
NECL2 ST17 BL2 SYNCAM IGSF4A Necl-2 SYNCAM1 RA175 |
| Synonyms name: |
nectin-like 2 |
| Locus: |
11q23, 3 |
| Discovery year: |
1998-11-02 |
| GenBank acession: |
AB017563 |
| Entrez gene record: |
23705 |
| Pubmed identfication: |
10610705 |
| RefSeq identity: |
NM_014333 |
| Classification: |
C2-set domain containing Immunoglobulin like domain containing V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000168202 |