| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IP3R |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the IP3R antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This IP3R antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q14643 |
| Purity: |
Antigen affinity |
| Description: |
Inositol 1, Mutations in ITPR1 cause spinocerebellar ataxia type 15, PRKG1, The product of the ITPR1 gene is predominantly enriched in cerebellar Purkinje cells but is also concentrated in neurons in the hippocampal CA1 region, This gene has been shown to interact with CA8, Upon stimulation by inositol 1, a disease associated with an heterogeneous group of cerebellar disorders, also known as IP3R or IP3R1, and FKBP1A, and cerebral cortex, caudate-putamen, is a protein that in humans is encoded by the ITPR1 gene, this receptor mediates calcium release from the endoplasmic reticulum, 4, 4, 4, 5-triphosphate (IP3) receptor is an intracellular IP3-gated calcium channel that modulates intracellular calcium signaling, 5-trisphosphate, 5-trisphosphate receptor type 1, Inositol 1 |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human IP3 receptor (TTQITEEVRDQLLEA) was used as the immunogen for this IP3R antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IP3R antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IP3R |
| Short name: |
IP3R Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
IP3R (Antibody to) |
| Alternative technique: |
antibodies |