| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PON2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the PON2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This PON2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q15165 |
| Purity: |
Antigen affinity |
| Description: |
Hydrolytic activity against acylhomoserine lactones and important bacterial quorum-sensing mediators suggests that PON2 may also play a role in defense responses to pathogenic bacteria, Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes, The encoded protein is ubiquitously expressed in human tissues, This gene encodes a member of the paraoxonase gene family, and may act as a cellular antioxidant, membrane-bound, protecting cells from oxidative stress, which includes three known members located adjacent to each other on the long arm of chromosome 7, Paraoxonase 2 is an enzyme that in humans is encoded by the PON2 gene |
| Immunogen: |
An amino acid sequence from the middle region of human Paraoxonase 2 (FLKYLETYLNLHWAN) was used as the immunogen for this PON2 antibody (100% mouse homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PON2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PON2 |
| Short name: |
PON2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PON2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9205 |
| Gene: |
PON2 |
More about : PON2 |
| Long gene name: |
paraoxonase 2 |
| Synonyms name: |
paraoxonase nirs arylesterase 2 |
| Locus: |
7q21, 3 |
| Discovery year: |
1995-05-25 |
| GenBank acession: |
M63012 AF001601 |
| Entrez gene record: |
5445 |
| Pubmed identfication: |
8661009 9714608 |
| RefSeq identity: |
NM_000305 |
| Classification: |
Paraoxonases |
| Havana BLAST/BLAT: |
OTTHUMG00000153948 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |