| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AVPR1A |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the AVPR1A antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This AVPR1A antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P30560 |
| Purity: |
Antigen affinity |
| Description: |
AVPR1A is present throughout the brain, It belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system, The protein encoded by this gene acts as receptor for arginine vasopressin, The receptor mediates cell contraction and proliferation, This gene is mapped to 12q14, V2R and OXT receptors, and vasculature, as well as in the periphery, in the liver, kidney, platelet aggregation, release of coagulation factor and glycogenolysis, 2, Arginine vasopressin receptor 1A(officially called AVPR1A) is one of the three major receptor types forarginine vasopressin(AVPR1BandAVPR2being the others) |
| Immunogen: |
An amino acid sequence from the middle region of rat AVPR1A (HPLKTLQQPARRSRLMIAT) was used as the immunogen for this AVPR1A antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the AVPR1A antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AVPR1A |
| Short name: |
AVPR1A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
arginine vasopressin receptor 1A (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AVPR V1a and AVPR1 and V1aR, AVPR1A and IDBG-44561 and ENSG00000166148 and 552, AVPR1A and IDBG-634667 and ENSBTAG00000007175 and 538439, Avpr1a and IDBG-193300 and ENSMUSG00000020123 and 54140, Plasma membranes, V1A vasopressin receptor binding, this GO :0001992 and regulation of systemic arterial blood pressure by vasopressin and biological process this GO :0002125 and maternal aggressive behavior and biological process this GO :0003084 and positive regulation of systemic arterial blood pressure and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005000 and vasopressin receptor activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006091 and generation of precursor metabolites and energy and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007202 and activation of phospholipase C activity and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007621 and negative regulation of female receptivity and biological process this GO :0007625 and grooming behavior and biological process this GO :0008015 and blood circulation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0010033 and response to organic substance and biological process this GO :0010035 and response to inorganic substance and biological process this GO :0010460 and positive regulation of heart rate and biological process this GO :0014049 and positive regulation of glutamate secretion and biological process this GO :0014902 and myotube differentiation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0017046 and peptide hormone binding and molecular function this GO :0019722 and calcium-mediated signaling and biological process this GO :0021537 and telencephalon development and biological process this GO :0030307 and positive regulation of cell growth and biological process this GO :0031394 and positive regulation of prostaglandin biosynthetic process and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0031894 and V1A vasopressin receptor binding and molecular function this GO :0032849 and positive regulation of cellular pH reduction and biological process this GO :0035176 and social behavior and biological process this GO :0035815 and positive regulation of renal sodium excretion and biological process this GO :0042631 and cellular response to water deprivation and biological process this GO :0042711 and maternal behavior and biological process this GO :0042713 and sperm ejaculation and biological process this GO :0043084 and penile erection and biological process this GO :0045777 and positive regulation of blood pressure and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0051412 and response to corticosterone and biological process this GO :0051970 and negative regulation of transmission of nerve impulse and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0005000 : vasopressin receptor activity and also this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0017046 : peptide hormone binding and also this GO :0031894 : V1A vasopressin receptor binding, this GO :0005000 : vasopressin receptor activity, this GO :0005080 : protein kinase C binding, this GO :0005515 : protein binding, this GO :0017046 : peptide hormone binding, this GO :0031894 : V1A vasopressin receptor binding, arginine vasopressin receptor 1A |
| Identity: |
895 |
| Gene: |
AVPR1A |
More about : AVPR1A |
| Long gene name: |
arginine vasopressin receptor 1A |
| Synonyms gene: |
AVPR1 |
| Locus: |
12q14, 2 |
| Discovery year: |
1992-02-28 |
| GenBank acession: |
L25615 |
| Entrez gene record: |
552 |
| Pubmed identfication: |
8106369 |
| Classification: |
Arginine vasopressin and oxytocin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000169980 |