| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RIP3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the RIP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This RIP3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y572 |
| Purity: |
Antigen affinity |
| Description: |
It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, The encoded protein is predominantly localized to the cytoplasm, The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, This gene is mapped to 14q12, also known as RIP3, and can induce apoptosis and weakly activate the NF-kappaB transcription factor, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals, and contains a C-terminal domain unique from other RIP family members, is an enzyme that in humans is encoded by the RIPK3 gene, Receptor-interacting serine/threonine-protein kinase 3(RIPK3) |
| Immunogen: |
An amino acid sequence from the N-terminus of human RIP3 (EVKAMASLDNEFVLRLE) was used as the immunogen for this RIP3 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RIP3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RIP3 |
| Short name: |
RIP3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RIP3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10021 |
| Gene: |
RIPK3 |
More about : RIPK3 |
| Long gene name: |
receptor interacting serine/threonine kinase 3 |
| Synonyms gene name: |
receptor-interacting serine-threonine kinase 3 |
| Synonyms: |
RIP3 |
| Locus: |
14q12 |
| Discovery year: |
1999-12-17 |
| GenBank acession: |
AF156884 |
| Entrez gene record: |
11035 |
| Pubmed identfication: |
10339433 10358032 |
| RefSeq identity: |
NM_006871 |
| Havana BLAST/BLAT: |
OTTHUMG00000029349 |