| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
GPR30 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Monkey , Mouse (Mus musculus), Rat, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the GPR30 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This GPR30 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q99527 |
| Purity: |
Antigen affinity |
| Description: |
Alternate transcriptional splice variants which encode the same protein have been characterized, GPR30 therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen, The protein binds estrogen, This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum, also known as the GPR30 or CEPR, is a G protein-coupled receptor that in humans is encode d by the GPER gene, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3, 4, 5-trisphosphate in the nucleus, G-protein coupled estrogen receptor 1 (GPER1) |
| Immunogen: |
An amino acid sequence from the C-terminus of human G-protein coupled receptor 30 (ENVFISVHLLQRTQ) was used as the immunogen for this GPR30 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the GPR30 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
GPR30 |
| Short name: |
GPR30 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GPR30 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4485 |
| Gene: |
GPER1 |
More about : GPER1 |
| Long gene name: |
G protein-coupled estrogen receptor 1 |
| Synonyms gene: |
CMKRL2 GPR30 GPER |
| Synonyms gene name: |
G protein-coupled receptor 30 |
| Synonyms: |
FEG-1 GPCR-Br LERGU LERGU2 DRY12 LyGPR CEPR |
| Locus: |
7p22, 3 |
| Discovery year: |
1997-06-12 |
| GenBank acession: |
U63917 |
| Entrez gene record: |
2852 |
| Pubmed identfication: |
9479505 17655271 |
| RefSeq identity: |
NM_001039966 |
| Classification: |
G protein-coupled estrogen receptor |
| Havana BLAST/BLAT: |
OTTHUMG00000023680 |