| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Apoptosis-Inducing Factor (Mitochondrial marker) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the Apoptosis-Inducing Factor antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Apoptosis-Inducing Factor antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O95831 |
| Purity: |
Antigen affinity |
| Description: |
A related pseudogene has been identified on chromosome 10, In addition, Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation, Mutations in this gene cause combined oxidative phosphorylation deficiency 6, This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, also known as AIF or PDCD8 is a protein that in humans is encoded by the AIFM1 gene, and it is found in the mitochondrial intermembrane space in healthy cells, mitochondrial, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9, which results in a severe mitochondrial encephalomyopathy, Apoptosis-inducing factor 1 |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human AIFM1 (EQHEDLNEVAKLFNIHED) was used as the immunogen for this Apoptosis-Inducing Factor antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Apoptosis-Inducing Factor antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Factor (Mitochondrial |
| Short name: |
Apoptosis-Inducing Factor Antibody (Mitochondrial ) |
| Technique: |
Component cell markers and DNA bp, Protein markers in kDA, antibodies against human proteins, antibodies for, markers are , Antibody, DNA sequences , chromosome , er genes or , genetic markers , species, that can be used to identify individuals or , with a known location on a |
| Alternative name: |
programmed cellular destruction-Inducing Factor (Antibody to) (Mitochondrial detection labelled) |
| Alternative technique: |
antibodies |