| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
EGR2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the EGR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This EGR2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P11161 |
| Purity: |
Antigen affinity |
| Description: |
Charcot-Marie-Tooth disease type 4E(CMT4E), Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D(CMT1D), EGR2 assists with SUMO1 conjugation to its coregulators NAB1 and NAB2, The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers, This gene is mapped to 10q21, and with Dejerine-Sottas syndrome(DSS), whose sumoylation down-regulates EGR2 own transcriptional activity, 3, Early growth response protein 2 is a protein that in humans is encoded by the EGR2 gene |
| Immunogen: |
An amino acid sequence from the N-terminus of human Early growth response protein 2 (TMSQTQPDLDHLYSPP) was used as the immunogen for this EGR2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the EGR2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
EGR2 |
| Short name: |
EGR2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
EGR2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3239 |
| Gene: |
EGR2 |
More about : EGR2 |
| Long gene name: |
early growth response 2 |
| Synonyms gene: |
KROX20 |
| Synonyms gene name: |
Drosophila) , early growth response 2 (Krox-20 homolog |
| Synonyms name: |
Drosophila , Krox-20 homolog |
| Locus: |
10q21, 3 |
| Discovery year: |
1988-08-31 |
| GenBank acession: |
BC035625 |
| Entrez gene record: |
1959 |
| RefSeq identity: |
NM_000399 |
| Classification: |
Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000018308 |
| Locus Specific Databases: |
Mutation Database of Inherited Peripheral Neuropathies LRG_239 |