| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
COL2A1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
IHC-F, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, Western blot: 0 |
| Notes: |
Titration of the COL2A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This COL2A1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P28481 |
| Purity: |
Antigen affinity |
| Description: |
It is a fibrillar collagen found in cartilage and the vitreous humor of the eye, also known as COL2A1, is the major collagen synthesized by chondrocytes, Collagen type 2 alpha 1 |
| Immunogen: |
An amino acid sequence from the C-terminus of mouse Collagen type 2 (AFAGLGQREKGPDPMQYMRA) was used as the immunogen for this COL2A1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the COL2A1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
COL2A1 |
| Short name: |
COL2A1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
a 1 (Antibody to), classification II, collagen |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ANFH and AOM and COL11A3 and SEDC and STL1, COL2A1 and IDBG-29355 and ENSG00000139219 and 1280, COL2A1 and IDBG-632928 and ENSBTAG00000013155 and 407142, Col2a1 and IDBG-179337 and ENSMUSG00000022483 and 12824, Extracellular, alpha 1, platelet-derived growth factor binding, this GO :0001501 and skeletal system development and biological process this GO :0001502 and cartilage condensation and biological process this GO :0001503 and ossification and biological process this GO :0001894 and tissue homeostasis and biological process this GO :0001958 and endochondral ossification and biological process this GO :0002062 and chondrocyte differentiation and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0005201 and extracellular matrix structural constituent and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005581 and collagen trimer and cellular component this GO :0005585 and collagen type II and cellular component this GO :0005604 and basement membrane and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0006029 and proteoglycan metabolic process and biological process this GO :0007411 and axon guidance and biological process this GO :0007417 and central nervous system development and biological process this GO :0007601 and visual perception and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030020 and extracellular matrix structural constituent conferring tensile strength and molecular function this GO :0030198 and extracellular matrix organization and biological process this GO :0030199 and collagen fibril organization and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0030903 and notochord development and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0035108 and limb morphogenesis and biological process this GO :0042472 and inner ear morphogenesis and biological process this GO :0042802 and identical protein binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0048407 and platelet-derived growth factor binding and molecular function this GO :0048705 and skeletal system morphogenesis and biological process this GO :0048839 and inner ear development and biological process this GO :0051216 and cartilage development and biological process this GO :0060021 and palate development and biological process this GO :0060174 and limb bud formation and biological process this GO :0060272 and embryonic skeletal joint morphogenesis and biological process this GO :0060348 and bone development and biological process this GO :0060351 and cartilage development involved in endochondral bone morphogenesis and biological process this GO :0071599 and otic vesicle development and biological process this GO :0071773 and cellular response to BMP stimulus and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0005201 : extracellular matrix structural constituent, this GO :0005201 : extracellular matrix structural constituent and also this GO :0005515 : protein binding and also this GO :0030020 : extracellular matrix structural constituent conferring tensile strength and also this GO :0042802 : identical protein binding and also this GO :0046872 : metal ion binding and also this GO :0048407 : platelet-derived growth factor binding, this GO :0005515 : protein binding, this GO :0030020 : extracellular matrix structural constituent conferring tensile strength, this GO :0042802 : identical protein binding, this GO :0046872 : metal ion binding, this GO :0048407 : platelet-derived growth factor binding, type II, collagen |
| Identity: |
2200 |
| Gene: |
COL2A1 |
More about : COL2A1 |
| Long gene name: |
collagen type II alpha 1 chain |
| Synonyms gene: |
SEDC AOM |
| Synonyms gene name: |
alpha 1 (primary osteoarthritis, alpha 1 collagen type II alpha 1 , collagen, congenital) arthroophthalmopathy, progressive (Stickler syndrome) collagen, spondyloepiphyseal dysplasia, type II, type II |
| Synonyms: |
STL1 |
| Locus: |
12q13, 11 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X16468 |
| Entrez gene record: |
1280 |
| Pubmed identfication: |
1677770 |
| RefSeq identity: |
NM_001844 |
| Classification: |
Collagens |
| Havana BLAST/BLAT: |
OTTHUMG00000149896 |
| Locus Specific Databases: |
Belgium , Ghent, LOVD - Center for Medical Genetics |