| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TAP2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the TAP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TAP2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q03519 |
| Purity: |
Antigen affinity |
| Description: |
ATP-binding cassette, TAP2 forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum, The TAP2 gene was assigned to human chromosome 6p21, The protein encoded by this gene is involved in antigen presentation, This gene is located 7 kb telomeric to gene family member ABCB2, major histocompatibility complex 2 is a membrane-associated protein and a member of the superfamily of ATP-binding cassette (ABC) transporters, 3, Transporter |
| Immunogen: |
An amino acid sequence from the C-terminus of human TAP2 (QRAHQILVLQEGKLQKLAQL) was used as the immunogen for this TAP2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TAP2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TAP2 |
| Short name: |
TAP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Uncharacterized protein (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ATPase activity, Plasma membranes, TAP-dependent and biological process this GO :0002485 and antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent and biological process this GO :0002489 and antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent and biological process this GO :0002504 and antigen processing and presentation of peptide or polysaccharide antigen via MHC class II and biological process this GO :0002591 and positive regulation of antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0005215 and transporter activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0006200 and ATP catabolic process and biological process this GO :0006810 and transport and biological process this GO :0006955 and immune response and biological process this GO :0015197 and peptide transporter activity and molecular function this GO :0015833 and peptide transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016887 and ATPase activity and molecular function this GO :0019882 and antigen processing and presentation and biological process this GO :0042613 and MHC class II protein complex and cellular component this GO :0042626 and ATPase activity, TAP2 and IDBG-403192 and ENSG00000250264 and, coupled to transmembrane movement of substances, coupled to transmembrane movement of substances, coupled to transmembrane movement of substances and molecular function this GO :0055085 and transmembrane transport and biological process, this GO :0002481 and antigen processing and presentation of exogenous protein antigen via MHC class Ib, this GO :0005215 : transporter activity, this GO :0005215 : transporter activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0015197 : peptide transporter activity and also this GO :0016887 : ATPase activity and also this GO :0042626 : ATPase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0015197 : peptide transporter activity, this GO :0016887 : ATPase activity, this GO :0042626 : ATPase activity, Uncharacterized protein |
| Identity: |
18655 |
| Gene: |
SEC14L3 |
More about : SEC14L3 |
| Long gene name: |
SEC14 like lipid binding 3 |
| Synonyms gene name: |
SEC14-like 3 (S, cerevisiae) SEC14-like lipid binding 3 |
| Synonyms: |
TAP2 |
| Synonyms name: |
tocopherol-associated protein 2 |
| Locus: |
22q12, 2 |
| Discovery year: |
2002-09-18 |
| GenBank acession: |
AY158086 |
| Entrez gene record: |
266629 |
| Pubmed identfication: |
12757856 15040456 17428729 |
| RefSeq identity: |
NM_174975 |
| Classification: |
SEC14 family |
| Havana BLAST/BLAT: |
OTTHUMG00000151259 |