| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ABCB4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the ABCB4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This ABCB4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P21439 |
| Purity: |
Antigen affinity |
| Description: |
ABCB4 gene mutations represent a genetic factor involved in this peculiar form of cholesterol gallstone disease in adults, MDR1 and MDR3/ABCB4 constitute the human P-glycoprotein gene family, The gene contains 28 exons and 27 of these contain coding sequences for the two homologous halves of the protein that correlate with functional domains, also called MDR3, is a protein that in humans is encoded by the ABCB4 gene, member 4 (ABCB4), Adenosine triphosphate-binding cassette subfamily B |
| Immunogen: |
An amino acid sequence from the N-terminus of human ABCB4 (MDLEAAKNGTAWRPTSAEGD) was used as the immunogen for this ABCB4 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ABCB4 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ABCB4 |
| Short name: |
ABCB4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ABCB4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
45 |
| Gene: |
ABCB4 |
More about : ABCB4 |
| Long gene name: |
ATP binding cassette subfamily B member 4 |
| Synonyms gene: |
PGY3 MDR3 |
| Synonyms gene name: |
ATP-binding cassette, member 4 , sub-family B (MDR/TAP) |
| Synonyms: |
MDR2 PFIC-3 GBD1 |
| Locus: |
7q21, 12 |
| Discovery year: |
1988-05-11 |
| GenBank acession: |
M23234 |
| Entrez gene record: |
5244 |
| Pubmed identfication: |
2892668 11313316 |
| RefSeq identity: |
NM_000443 |
| Classification: |
ATP binding cassette subfamily B |
| Havana BLAST/BLAT: |
OTTHUMG00000023396 |