| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
WISP1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the WISP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This WISP1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O95388 |
| Purity: |
Antigen affinity |
| Description: |
2001), By use of radiation hybrid mapping panels, It is induced by WNT1 and belongs to the CCN family, Pennica et al, Pennica et al, WISP1 genomic DNA was amplified in colon cancer cell lines and in human colon tumors, also known as CCN4, and its RNA was overexpressed in 84% of tumors examined compared with patient-matched normal mucosa, and nephroblastoma overexpressed(Tanaka et al, cysteine-rich-61, is a matricellular protein that in humans is encoded by the WISP1 gene, roughly 4 Mb distal to MYC, which includes connective tissue growth factor, (1998) found that two distinct systems demonstrated that WISP1 induction was associated with expression of WNT1, (1998) mapped the gene to chromosome 8q24, 1-q24, 3, WNT1-Inducible Signaling Pathway Protein 1 |
| Immunogen: |
An amino acid sequence from the C-terminus of human WNT1-Inducible Signaling Pathway Protein 1 (ADLESYPDFSEIAN) was used as the immunogen for this WISP1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the WISP1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
WISP1 |
| Short name: |
WISP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 1 inducible signaling pathway protein 1 (Antibody to), wingless-classification MMTV integration site family |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, WISP1 and IDBG-36325 and ENSG00000104415 and 8840, WISP1 and IDBG-644060 and ENSBTAG00000000707 and 539163, Wisp1 and IDBG-146803 and ENSMUSG00000005124 and 22402, insulin-like growth factor binding, this GO :0001558 and regulation of cell growth and biological process this GO :0005515 and protein binding and molecular function this GO :0005520 and insulin-like growth factor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0016055 and Wnt signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005520 : insulin-like growth factor binding, this GO :0005520 : insulin-like growth factor binding, WNT1 inducible signaling pathway protein 1 |
| Identity: |
12769 |
| Gene: |
WISP1 |
More about : WISP1 |
| Long gene name: |
WNT1 inducible signaling pathway protein 1 |
| Synonyms: |
CCN4 |
| Locus: |
8q24, 22 |
| Discovery year: |
1999-01-22 |
| GenBank acession: |
AF100779 |
| Entrez gene record: |
8840 |
| Pubmed identfication: |
9843955 |
| RefSeq identity: |
NM_003882 |
| Classification: |
CYR61/CTGF/NOV matricellular proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000164440 |