| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Factor VIII |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Factor VIII antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Factor VIII antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P00451 |
| Purity: |
Antigen affinity |
| Description: |
1984, 1994), By in situ hybridization, Factor VIII is activated proteolytically by a variety of coagulation enzymes, Hoyer, It is tightly associated in the blood with VWF, Tantravahi et al, The F8 gene encodes coagulation Factor VIII, a large plasma glycoprotein that functions in the blood coagulation cascade as a cofactor for the F9a-dependent activation of F10, including thrombin(F2), which serves as a protective carrier protein for Factor VIII (Toole et al, (1986) concluded that the F8 gene is located in the proximal part of chromosome Xq28 with probes DX13 and St14 distally located, Coagulation Factor VIII (FVIII) is an essential blood-clotting protein |
| Immunogen: |
An amino acid sequence from the middle region of human F8 (APVLQDFRSLNDSTN) was used as the immunogen for this Factor VIII antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Factor VIII antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Factor VIII |
| Short name: |
Factor VIII Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Factor VIII (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2294 |
| Gene: |
COX8A |
More about : COX8A |
| Long gene name: |
cytochrome c oxidase subunit 8A |
| Synonyms gene: |
COX8 |
| Synonyms gene name: |
cytochrome c oxidase subunit VIII cytochrome c oxidase subunit VIIIA (ubiquitous) |
| Synonyms: |
COX8-2 COX8L VIII-L COX VIII |
| Locus: |
11q13, 1 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
J04823 |
| Entrez gene record: |
1351 |
| Pubmed identfication: |
2543673 2847943 |
| RefSeq identity: |
NM_004074 |
| Classification: |
Mitochondrial complex IV: cytochrome c oxidase subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000167785 |