| Also known as: |
von Willebrand Factor |
| Other names: |
coagulation factor VIII VWF, von Willebrand antigen II, von Willebrand factor, von Willebrand factor, von Willebrand factor, von Willebrand factor preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
VWF |
| Other gene names: |
F8VWF, F8VWF, VWD, VWF, vWF, VWF |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, kappa + IgG1, IgG1 |
| Clone: |
3E2D10 + VWF635 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation, It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen, Kaposi's sarcoma and cardiac myxoma, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, This particular antibody might cross react with speacies outside of the listed ones, e, including cleavage of the propeptide and formation of N-terminal disulfide bonds, plasma and platelets, vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, g, von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS) |
| Gene target: |
von Willebrand Factor/ Factor VIII Related-Ag |
| Short name: |
von Willebrand Factor/ Factor VIII -Ag |
| Alternative name: |
von Willebrand Factor/ Factor VIII Related-Ag |
| Identity: |
2294 |
| Gene: |
COX8A |
More about : COX8A |
| Long gene name: |
cytochrome c oxidase subunit 8A |
| Synonyms gene: |
COX8 |
| Synonyms gene name: |
cytochrome c oxidase subunit VIII cytochrome c oxidase subunit VIIIA (ubiquitous) |
| Synonyms: |
COX8-2 COX8L VIII-L COX VIII |
| Locus: |
11q13, 1 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
J04823 |
| Entrez gene record: |
1351 |
| Pubmed identfication: |
2543673 2847943 |
| RefSeq identity: |
NM_004074 |
| Classification: |
Mitochondrial complex IV: cytochrome c oxidase subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000167785 |