| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PER1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the PER1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This PER1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O15534 |
| Purity: |
Antigen affinity |
| Description: |
By fluorescence in situ hybridization, Drosophila, Homolog of, RNA abundance of rigui changed 2, Shigeyoshi et al, Sun et al, Sun et al, They found that Per1 is rapidly induced by short duration exposure to light at levels sufficient to reset the clock, Von Gall et al, also known as PER or RIGUI, designated mouse Per1 by them, expression rose during the light period and fell during the dark period, i, is a protein that in humans is encoded by the PER1 gene, the expression of rigui oscillated over a 24-hour period, which exhibits robust rhythmic expression in the SCN, which occurs through the nocturnal activation of melatonin mt1 receptors, with highest expression at onset of dark in a 12-hour light/dark cycle, (1997) examined the effects of light on rigui, (1997) found that in mouse retina, (1997) mapped the human PER1 gene to 17p12, (2002) demonstrated that cycling expression of the clock gene Per1 in rodent pituitary cells depends on the heterologous sensitization of the adenosine A2B receptor, 9-fold between highest and lowest levels in mouse retina, Period, e |
| Immunogen: |
An amino acid sequence from the N-terminus of human PER-1(RDFTQEKSVFCRIR) was used as the immunogen for this PER1 antibody (100% mouse homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PER1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PER1 |
| Short name: |
PER1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PER1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8845 |
| Gene: |
PER1 |
More about : PER1 |
| Long gene name: |
period circadian clock 1 |
| Synonyms gene: |
PER |
| Synonyms gene name: |
period (Drosophila) homolog 1 period homolog 1 (Drosophila) |
| Synonyms: |
RIGUI |
| Locus: |
17p13, 1 |
| Discovery year: |
1997-10-21 |
| GenBank acession: |
AB002107 |
| Entrez gene record: |
5187 |
| Pubmed identfication: |
9323128 |
| Havana BLAST/BLAT: |
OTTHUMG00000178317 |