| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Hepsin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Hepsin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Hepsin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P05981 |
| Purity: |
Antigen affinity |
| Description: |
Dhanasekaran et al, Guipponi et al, In 3 different human cell lines, Signature expression profiles of normal adjacent prostate, Tsuji et al, Using cDNA microarrays, also known as TMPRSS1, and metastatic, benign prostatic hypertrophy, hormone-refractory prostate cancer were determined, is an enzyme that in humans is encoded by the HPN gene, localized prostate cancer, (1991) mapped the gene to 19q11-q13, (2001) examined gene expression profiles of more than 50 normal and neoplastic prostate specimens and 3 common prostate cancer cell lines, (2008) found that Hepsin was stably anchored in the endoplasmic reticulum, 2, Hepsin |
| Immunogen: |
An amino acid sequence from the C-terminus of human Hepsin (KVSDFREWIFQAIKTHSEA) was used as the immunogen for this Hepsin antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Hepsin antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Hepsin |
| Short name: |
Hepsin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Hepsin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5155 |
| Gene: |
HPN |
More about : HPN |
| Long gene name: |
hepsin |
| Synonyms: |
TMPRSS1 |
| Synonyms name: |
serine 1 , transmembrane protease |
| Locus: |
19q13, 11 |
| Discovery year: |
1992-12-07 |
| Entrez gene record: |
3249 |
| Pubmed identfication: |
2835076 |
| RefSeq identity: |
NM_002151 |
| Classification: |
Proteases, serine |
| Havana BLAST/BLAT: |
OTTHUMG00000182474 |