| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CXCR5 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the CXCR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This CXCR5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P32302 |
| Purity: |
Antigen affinity |
| Description: |
Chan et al, In humans, Reif et al, The gene plays an essential role in B cell migration, also known as BLR1, and established that cell position in vivo can be determined by the balance of responsiveness to chemoattractants made in separate but adjacent zones, is a G protein-coupled seven transmembrane receptor for chemokine CXCL13 (also known as BLC) and belongs to the CXC chemokine receptor family, the protein is encoded by the CXCR5 gene, (2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, (2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma(PIOL), Chemokine CXC Motif Receptor 5 |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human Chemokine CXC Motif Receptor 5 (SSLSESENATSLTTF) was used as the immunogen for this CXCR5 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CXCR5 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CXCR5 |
| Short name: |
CXCR5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-X-C motif) receptor 5 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BLR1 and CD185 and MDR15, BLR1 and IDBG-631448 and ENSBTAG00000046320 and 497021, C-X-C chemokine receptor activity, CXCR5 and IDBG-74047 and ENSG00000160683 and 643, Cell surfaces, Cxcr5 and IDBG-157659 and ENSMUSG00000047880 and 12145, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006928 and cellular component movement and biological process this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0032467 and positive regulation of cytokinesis and biological process this GO :0042113 and B cell activation and biological process this GO :0048535 and lymph node development and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0005515 : protein binding and also this GO :0016494 : C-X-C chemokine receptor activity, this GO :0005515 : protein binding, this GO :0016494 : C-X-C chemokine receptor activity, chemokine (C-X-C motif) receptor 5 |
| Identity: |
1060 |
| Gene: |
CXCR5 |
More about : CXCR5 |
| Long gene name: |
C-X-C motif chemokine receptor 5 |
| Synonyms gene: |
BLR1 |
| Synonyms gene name: |
Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) chemokine (C-X-C motif) receptor 5 , GTP-binding protein Burkitt lymphoma receptor 1 |
| Synonyms: |
MDR15 CD185 |
| Locus: |
11q23, 3 |
| Discovery year: |
1993-06-29 |
| GenBank acession: |
X68829 |
| Entrez gene record: |
643 |
| Pubmed identfication: |
1425907 |
| RefSeq identity: |
NM_001716 |
| Classification: |
CD molecules C-X-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000166345 |