| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRAF1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the TRAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TRAF1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13077 |
| Purity: |
Antigen affinity |
| Description: |
Both LAP1 and TRAF1 associated with the cytoplasmic domain of p80/TNFR2 in vivo, LMP1 expression redirects LAP1 and TRAF1 from scattered cytoplasmic structures to LMP1 plasma membrane patches, Mosialos et al, Siemienski et al, The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family, also called EBI6, is a protein that in humans is encoded by the TRAF1 gene, specifically associates with LAP1 (TRAF3) or TRAF1 in B lymphoblasts, the EBV-transforming protein, (1995) found that LMP1, (1997) used fluorescence in situ hybridization to map the gene to 9q33-q34, TNF Receptor-Associated Factor 1 |
| Immunogen: |
An amino acid sequence from the middle region of human TNF Receptor-Associated Factor 1 (HQSQLDRERILSLEQR) was used as the immunogen for this TRAF1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRAF1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRAF1 |
| Short name: |
TRAF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
tumor necrosis factor receptor-associated factor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, EBI6 and MGC:10353, TRAF1 and IDBG-638832 and ENSBTAG00000003012 and 540944, TRAF1 and IDBG-83153 and ENSG00000056558 and 7185, Traf1 and IDBG-163730 and ENSMUSG00000026875 and 22029, thioesterase binding, this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031996 and thioesterase binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :2001236 and regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0031996 : thioesterase binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0031996 : thioesterase binding, TNF receptor-associated factor 1 |
| Identity: |
12031 |
| Gene: |
TRAF1 |
More about : TRAF1 |
| Long gene name: |
TNF receptor associated factor 1 |
| Synonyms: |
EBI6 |
| Locus: |
9q33, 2 |
| Discovery year: |
1997-06-12 |
| GenBank acession: |
AK090468 |
| Entrez gene record: |
7185 |
| Pubmed identfication: |
8069916 |
| RefSeq identity: |
NM_005658 |
| Classification: |
TNF receptor associated factors |
| Havana BLAST/BLAT: |
OTTHUMG00000020578 |