| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRIF |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the TRIF antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TRIF antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q80UF7 |
| Purity: |
Antigen affinity |
| Description: |
AP1, By coimmunoprecipitation analysis, By genomic sequence analysis, Functional analysis showed that the association of TLR3 and TICAM1 mediates dsRNA activation of IFNB, It mediates the rather delayed cascade of two TLR-associated signaling cascades, Oshiumi et al, Oshiumi et al, Small interfering(si)RNA blockage of TICAM1, TICAM1 activation of NFKB was found to occur predominantly through IRAK1 rather than IRAK2 , also known as TRIF, but not with other TLRs, is an adapter in responding to activation of toll-like receptors(TLRs), just upstream of the TIR domain, or IRF3, reduced IFNB production in response to dsRNA, through either NFKB, where the other one is dependent upon a MyD88 adapter, (2003) mapped the TICAM1 gene to chromosome 19p13, (2003) showed that TICAM1 interacts specifically with TLR3, 3, TICAM1 (TIR domain-containing adaptor molecule 1) |
| Immunogen: |
An amino acid sequence from the C-terminus of mouse TRIF (NNHMWGHTGAQSSDDK) was used as the immunogen for this TRIF antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRIF antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRIF |
| Short name: |
TRIF Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TRIF (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17857 |
| Gene: |
TRIM69 |
More about : TRIM69 |
| Long gene name: |
tripartite motif containing 69 |
| Synonyms gene: |
RNF36 |
| Synonyms gene name: |
ring finger protein 36 tripartite motif-containing 69 |
| Synonyms: |
Trif TRIMLESS |
| Locus: |
15q15-q21 |
| Discovery year: |
2002-01-10 |
| GenBank acession: |
AF302088 |
| Classification: |
Ring finger proteins Tripartite motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000131246 |