| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
LTK |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the LTK antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This LTK antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P29376 |
| Purity: |
Antigen affinity |
| Description: |
Liao et al, The protein encoded by this gene is a member of the ALK/LTK receptor family of receptor tyrosine kinases (RTKs) whose ligand is unknown, Thus, Toyoshima et al, also known as TYK1, is an enzyme that in humans is encoded by the LTK gene, the gene produces not only the putative receptor tyrosine kinase for an unknown ligand but also multiple protein products that may have different functions, (1993) cloned a set of cDNAs representing differently spliced human LTK mRNAs, (1996) found that the mouse Ltk gene is closely linked to the Tyro3 gene which maps to mouse chromosome 2, Leukocyte tyrosine kinase |
| Immunogen: |
An amino acid sequence from the C-terminus of human Leukocyte tyrosine kinase (RGLQPQNLWNPTYRS) was used as the immunogen for this LTK antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the LTK antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
LTK |
| Short name: |
LTK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
leukocyte receptor tyrosine kinase (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
LTK and IDBG-7133 and ENSG00000062524 and 4058, Ltk and IDBG-199622 and ENSMUSG00000027297 and 17005, Plasma membranes, TYK1, this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008283 and cell proliferation and biological process this GO :0010666 and positive regulation of cardiac muscle cell apoptotic process and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0071300 and cellular response to retinoic acid and biological process, leukocyte receptor tyrosine kinase |
| Identity: |
6721 |
| Gene: |
LTK |
More about : LTK |
| Long gene name: |
leukocyte receptor tyrosine kinase |
| Synonyms gene name: |
leukocyte tyrosine kinase |
| Synonyms: |
TYK1 |
| Locus: |
15q15, 1 |
| Discovery year: |
1991-06-28 |
| GenBank acession: |
D16105 |
| Entrez gene record: |
4058 |
| Pubmed identfication: |
2320375 |
| Classification: |
Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000130339 |