| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRPV3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the TRPV3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TRPV3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q8NET8 |
| Purity: |
Antigen affinity |
| Description: |
Peier et al, Peier et al, The protein belongs to a family of nonselective cation channels that function in a variety of processes, They determined that it is a cation-permeable channel activated by warm and hot temperatures, They mapped the mouse gene to chromosome 11B4, Xu et al, also known as VRL3, including temperature sensation and vasoregulation, is encoded by the TRPV3 gene, (2002) localized the gene to a BAC clone mapped to chromosome 17p13, (2002) showed that increasing temperature from approximately 22 to 40 degrees Celsius in mammalian cells transfected with human TRPV3 elevated intracellular calcium by activating a nonselective cationic conductance, (2002) stably expressed mouse Trpv3 in Chinese hamster ovary cells and assayed electrophysiologic activity by whole cell voltage-clamp techniques, Transient Receptor Potential Cation Channel Subfamily V Member 3 |
| Immunogen: |
Amino acids (757-773 RRTDFNKIQDSSRNNSK-human) were used as the immunogen for this TRPV3 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRPV3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRPV3 |
| Short name: |
TRPV3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TRPV3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18084 |
| Gene: |
TRPV3 |
More about : TRPV3 |
| Long gene name: |
transient receptor potential cation channel subfamily V member 3 |
| Synonyms gene name: |
member 3 , subfamily V, transient receptor potential cation channel |
| Synonyms: |
VRL3 |
| Locus: |
17p13, 2 |
| Discovery year: |
2002-07-05 |
| GenBank acession: |
AF514998 |
| Entrez gene record: |
162514 |
| Pubmed identfication: |
12016205 12077606 16382100 |
| RefSeq identity: |
NM_145068 |
| Classification: |
Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000090695 |