| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CUEDC2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the CUEDC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This CUEDC2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9H467 |
| Purity: |
Antigen affinity |
| Description: |
CUEDC2 reduced PRB protein content and promoted progesterone-induced PRB degradation via the ubiquitin-proteasome pathway, Hartz(2011) mapped the CUEDC2 gene to chromosome 10q24, Mutation analysis revealed that the IF domain of PRB and the CUE domain of CUEDC2 were required for the interaction, Using coimmunoprecipitation analysis and protein pull-down assays, Zhang et al, or PGR) and estrogen receptor(ER)-alpha, (2007) confirmed that CUEDC2 interacted with the PRB isoform of PR, 32 based on an alignment of the sequence with the genomic sequence (GRCh37), Cue Domain-Containing Protein 2 is involved in ubiquitin-and proteasome-mediated degradation of progesterone receptor (PR |
| Immunogen: |
An amino acid sequence from the C-terminus of human Cue Domain-Containing Protein 2 (EAEEMKATYINLKPARKYRFH) was used as the immunogen for this CUEDC2 antibody (100% mouse homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CUEDC2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CUEDC2 |
| Short name: |
CUEDC2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CUEDC2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
28352 |
| Gene: |
CUEDC2 |
More about : CUEDC2 |
| Long gene name: |
CUE domain containing 2 |
| Synonyms gene: |
C10orf66 |
| Synonyms gene name: |
chromosome 10 open reading frame 66 |
| Synonyms: |
MGC2491 |
| Locus: |
10q24, 32 |
| Discovery year: |
2004-01-28 |
| GenBank acession: |
BC000262 |
| Entrez gene record: |
79004 |
| Pubmed identfication: |
24685480 |
| RefSeq identity: |
NM_024040 |
| Havana BLAST/BLAT: |
OTTHUMG00000018958 |