| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CD31 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the CD31 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CD31 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P16284 |
| Purity: |
Antigen affinity |
| Description: |
CD31 is found on the surface of platelets, Gumina et al, It is a member of the immunoglobulin(Ig) superfamily that is expressed on the surface of circulating platelets, Several adhesion molecules expressed on platelets and endothelium also localized to 17q, Using a PCR-based analysis of somatic cell hybrids, Xie and Muller(1996) mapped the Pecam1 gene to mouse chromosome 6, also known as cluster of differentiation 31 (CD31) is a protein that in human is encoded by the PECAM1 gene found on chromosome 17, and it plays a key role in removing aged neutrophils from the body, and makes up a large portion of endothelial cell intercellular junctions, and particular T-cell subsets, and some types of T-cells, by fluorescence in situ hybridization, monocytes, monocytes, neutrophils, neutrophils, region F3-G1, (1996) mapped CD31 to chromosome 17 in the region 17q23-qter, PECAM-1 (Platelet endothelial cell adhesion molecule) |
| Immunogen: |
An amino acid sequence from the C-terminus of human CD31 (RKAVPDAVESRYSRTE) was used as the immunogen for this CD31 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CD31 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CD31 |
| Short name: |
CD31 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD31 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8823 |
| Gene: |
PECAM1 |
More about : PECAM1 |
| Long gene name: |
platelet and endothelial cell adhesion molecule 1 |
| Synonyms gene name: |
platelet/endothelial cell adhesion molecule 1 |
| Synonyms: |
CD31 |
| Synonyms name: |
CD31 antigen |
| Locus: |
17q23, 3 |
| Discovery year: |
1995-11-29 |
| GenBank acession: |
L34631 M37780 |
| Entrez gene record: |
5175 |
| Pubmed identfication: |
8661055 1690453 |
| RefSeq identity: |
NM_000442 |
| Classification: |
CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000175829 |