| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
KLF2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the KLF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This KLF2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q60843 |
| Purity: |
Antigen affinity |
| Description: |
Buckley et al, KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1(S1PR1) and the selectin CD62L, Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors, They concluded that LKLF functions, also known as LKLF (Lung Kruppel-like zinc finger transcription factor), and reduced expression of activation markers, by negatively regulating a MYC-dependent pathway, decreases in cell size and protein synthesis, in part, is a protein that in humans is encoded by the KLF2 gene, (2001) showed that expression of LKLF in a T-cell line induced reversible quiescence resulting in marked inhibition of proliferation, Krueppel-like factor 2 |
| Immunogen: |
An amino acid sequence from the N-terminus of mouse Kruppel-like factor 2 (ERGLQERWPRNEPE) was used as the immunogen for this KLF2 antibody (100% rat homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the KLF2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
KLF2 |
| Short name: |
KLF2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Kruppel-like factor 2 (lung) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0034101 and erythrocyte homeostasis and biological process this GO :0034616 and response to laminar fluid shear stress and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0036003 and positive regulation of transcription from RNA polymerase II promoter in response to stress and biological process this GO :0040029 and regulation of gene expression, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0051247 and positive regulation of protein metabolic process and biological process this GO :0060509 and Type I pneumocyte differentiation and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071409 and cellular response to cycloheximide and biological process this GO :0071499 and cellular response to laminar fluid shear stress and biological process this GO :1901653 and cellular response to peptide and biological process, KLF2 and IDBG-35485 and ENSG00000127528 and 10365, Klf2 and IDBG-167841 and ENSMUSG00000055148 and 16598, LKLF, epigenetic and biological process this GO :0043249 and erythrocyte maturation and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045893 and positive regulation of transcription, metal ion binding, nuclei, this GO :0000902 and cell morphogenesis and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046872 : metal ion binding, Kruppel-like factor 2 (lung) |
| Identity: |
6347 |
| Gene: |
KLF2 |
More about : KLF2 |
| Long gene name: |
Kruppel like factor 2 |
| Synonyms gene name: |
Kruppel-like factor 2 (lung) |
| Synonyms: |
LKLF |
| Synonyms name: |
lung Kruppel-like factor |
| Locus: |
19p13, 11 |
| Discovery year: |
1999-12-14 |
| GenBank acession: |
AF123344 |
| Entrez gene record: |
10365 |
| Pubmed identfication: |
10217429 10458913 |
| Classification: |
Kruppel like factors Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000182330 |