| Catalog number: | R31017 |
|---|---|
| Price: | 412 € |
| Supplier: | abbex |
| Product name: | Iduronate 2 sulfatase Antibody |
| Quantity: | 10 μg |
| Other quantities: | 0.1ml 263€ |
| Related search: |
| Category: | Antibody |
|---|---|
| Concentration: | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: | Antigen affinity purified |
| Conjugation: | Unconjugated |
| Clone: | Polyclonal antibody |
| Recognised antigen: | Iduronate 2 sulfatase |
| Host animal: | Rabbit (Oryctolagus cuniculus) |
| Clonality: | Polyclonal (rabbit origin) |
| Species reactivity: | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: | Titration of the Iduronate 2 sulfatase antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: | This Iduronate 2 sulfatase antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: | P22304 |
| Purity: | Antigen affinity |
| Description: | B, F9, Faust et al, IDS is involved in the lysosomal degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate, IDS is required for the lysosomal degradation of heparan sulfate and dermatan sulfate, Iduronate 2 sulfatase has a strong sequence homology with human arylsulfatases A, Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, Wilson et al, also known as Hunter syndrome, and C, and GABRA3 genes, and human glucosamine-6sulfatase, distal to the fragile X site, (1991) used an IDS cDNA clone to localize the gene to Xq28, (1992) and Daniele et al, (1993) demonstrated that the homologous Ids gene in the mouse occupies the same position on the X chromosome in relation to the FMR1, Iduronate 2 sulfatase (IDS) is an enzyme associated with Hunter syndrome |
| Immunogen: | An amino acid sequence from the C-terminus of human IDS (ELCREGKNLLKHFRFRDLE) was used as the immunogen for this Iduronate 2 sulfatase antibody |
| Storage: | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Iduronate 2 sulfatase antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: | Iduronate 2 sulfatase |
| Short name: | Iduronate 2 sulfatase Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | Iduronate 2 sulfatase (Antibody to) |
| Alternative technique: | antibodies |
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