| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
DLL3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the DLL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This DLL3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9NYJ7 |
| Purity: |
Antigen affinity |
| Description: |
2000), Dunwoodie et al, EGF repeats, In humans, Mutation in the mouse delta-like 3 gene, The human gene was identified within a critical interval, This family functions as Notch ligands that are characterized by a DSL domain, This gene encodes a member of the delta protein ligand family, This residue is highly conserved in Delta proteins from Drosophila to humans, and a transmembrane domain, and the substitution of a charged polar for a nonpolar residue may disrupt the conformation of the DLL3 protein, mapped in two consanguineous Arab-Israeli and Pakistani SCDO1 pedigrees, of 7, result in abnormal segmentation of the vertebral column suggests that the segmentation clock also acts during human embryonic development, results in the mouse 'pudgy' phenotype, such as DLL3, the fact that mutations in genes required for oscillation, which is homologous to the Notch-ligand delta in Drosophila, (1997) presented results suggesting that mouse DLL3 may complement the function of other delta homologs during early pattern formation in the mouse embryo, 1-q13, 3 between D19S570 and D19S908(Bulman et al, 8 cM at 19q13, Delta-like 3 is a protein which in humans is encoded by the DLL3 gene |
| Immunogen: |
Amino acids 599-618 (RAGQRQHLLFPYPSSILSVK-human) were used as the immunogen for this DLL3 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DLL3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
DLL3 |
| Short name: |
DLL3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DLL3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2909 |
| Gene: |
DLL3 |
More about : DLL3 |
| Long gene name: |
delta like canonical Notch ligand 3 |
| Synonyms gene name: |
delta (Drosophila)-like 3 delta-like 3 (Drosophila) |
| Synonyms: |
SCDO1 |
| Locus: |
19q13, 2 |
| Discovery year: |
2000-03-15 |
| GenBank acession: |
AF241373 |
| Entrez gene record: |
10683 |
| Pubmed identfication: |
10364530 10742114 |
| Havana BLAST/BLAT: |
OTTHUMG00000183067 |