| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Syndecan 2 (HSPG) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Syndecan 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Syndecan 2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P34741 |
| Purity: |
Antigen affinity |
| Description: |
Bobardt et al, By Southern hybridization to a panel of human-mouse somatic cell hybrid DNA and by in situ hybridization, Flow cytometric analysis demonstrated SDC expression on endothelial cells, HIV bound to SDC on endothelial cell lines maintained its infectivity for at least 1 week, HSPG, HSPG1, Marynen et al, The protein encoded by this gene is a transmembrane(type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family, also known as SYND2, and Fibroglycan, can function as in trans HIV receptors via binding of HIV-1 gp120 to the syndecan heparan sulfate chains, compared with less than 1 day for unbound virus, including SDC2, is a protein that in humans is encoded by the SDC2 gene, (1989) showed that the heparan sulfate proteoglycan core protein maps to 8q22-q24, (2003) demonstrated that syndecans, (2003) suggested that SDC-rich endothelial cells lining the vasculature can provide a microenvironment that boosts HIV replication in T cells, (Heparan sulfate proteoglycan of basement membrane appears to be encoded by a gene on human chromosome 1, Bobardt et al, Syndecan-2 |
| Immunogen: |
An amino acid sequence from the middle region of human Syndecan 2/HSPG (EETDKEKVHLSDSERKMD) was used as the immunogen for this Syndecan 2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Syndecan 2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Syndecan 2 (HSPG) |
| Short name: |
Syndecan 2 Antibody (HSPG) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Syndecan 2 (Antibody to) (HSPG) |
| Alternative technique: |
antibodies |
| Identity: |
10659 |
| Gene: |
SDC2 |
More about : SDC2 |
| Long gene name: |
syndecan 2 |
| Synonyms gene: |
HSPG HSPG1 |
| Synonyms gene name: |
cell surface-associated , heparan sulfate proteoglycan 1 |
| Synonyms: |
fibroglycan SYND2 CD362 |
| Synonyms name: |
syndecan proteoglycan 2 |
| Locus: |
8q22, 1 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
BC030133 |
| Entrez gene record: |
6383 |
| Pubmed identfication: |
8187643 |
| RefSeq identity: |
NM_002998 |
| Classification: |
CD molecules Syndecans |
| Havana BLAST/BLAT: |
OTTHUMG00000164689 |