| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MCM6 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the MCM6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This MCM6 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q14566 |
| Purity: |
Antigen affinity |
| Description: |
6 is a protein that in humans is encoded by the MCM6 gene, An approximately 200-kb region surrounding the C/T(-13910) polymorphism in MCM6 intron 13 functioned as an enhancer of the lactase gene promoter in intestinal cell culture, It is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication, MCM6 has recently been shown to interact strongly Cdt1 at defined residues by mutating these target residues, The MCM genes were originally identified in yeast defective in minichromosome maintenance and have since been shown to play roles in the progression of the cell cycle, Wei et al, homolog of, many are cell division control genes, observed lack of Cdt1 recruitment of MCM2-7 to the pre-RC, pombe, s, Minichromosome maintenance |
| Immunogen: |
An amino acid sequence from the middle region of human MCM6 (ESEDFIVEQYKHLRQRD) was used as the immunogen for this MCM6 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MCM6 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MCM6 |
| Short name: |
MCM6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MCM6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6949 |
| Gene: |
MCM6 |
More about : MCM6 |
| Long gene name: |
minichromosome maintenance complex component 6 |
| Synonyms gene name: |
S, S, cerevisiae) , cerevisiae) minichromosome maintenance deficient 6 homolog (S, minichromosome maintenance deficient (mis5, pombe) (S, pombe) 6 MCM6 minichromosome maintenance deficient 6 (MIS5 homolog |
| Synonyms: |
Mis5 |
| Synonyms name: |
MIS5 homolog (S, pombe) |
| Locus: |
2q21, 3 |
| Discovery year: |
1996-06-14 |
| Entrez gene record: |
4175 |
| RefSeq identity: |
NM_005915 |
| Classification: |
MCM family |
| Havana BLAST/BLAT: |
OTTHUMG00000131739 |