| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
COX2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the COX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This COX2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P35354 |
| Purity: |
Antigen affinity |
| Description: |
Deletion of the murine gene in Min mice reduced the incidence of intestinal tumors, The COX2 gene encodes an inducible prostaglandin synthase enzyme that is overexpressed in adenocarcinomas and other tumors, suggesting that it is required for tumorigenesis, Cyclooxygenase (COX) is the key enzyme in conversion of arachidonic acid to PGs |
| Immunogen: |
Amino acids 589-604 (DDINPTVLLKERSTEL-human) were used as the immunogen for this COX2 antibody |
| Storage: |
After reconstitution, Avoid repeated freezing and thawing, Celcius or lower, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, The lyophilized COX2 antibody can be stored at 4oC to -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
COX2 |
| Short name: |
COX2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
COX2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9605 |
| Gene: |
PTGS2 |
More about : PTGS2 |
| Long gene name: |
prostaglandin-endoperoxide synthase 2 |
| Synonyms gene name: |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| Synonyms: |
COX2 |
| Synonyms name: |
prostaglandin G/H synthase 2 cyclooxygenase 2 |
| Locus: |
1q31, 1 |
| Discovery year: |
1992-10-28 |
| GenBank acession: |
D28235 |
| Entrez gene record: |
5743 |
| Pubmed identfication: |
1380156 |
| RefSeq identity: |
NM_000963 |
| Havana BLAST/BLAT: |
OTTHUMG00000035473 |