| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
GLUT4 (Glucose Transporter 4) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the GLUT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This GLUT4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P14672 |
| Purity: |
Antigen affinity |
| Description: |
A similar pattern of defects cause insulin resistance in human adipocytes, Glucose transporter 4 is a insulin-responsive glucose transporter, Human insulin resistance involves a defect in GLUT4 traffic and targeting leading to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface, Insulin alters the subcellular localization of GLUT4 vesicles in human muscle, It belongs to solute carrier family 2, and that this effect is impaired equally in insulin-resistant subjects with and without diabetes, member 1, Facilitated glucose transport by mammalian cells is not a property of a single protein but an activity associated with a family of structurally related proteins |
| Immunogen: |
mouse and rat), Amino acids 491-509 (EQEVKPSTELEYLGPDEND) were used as the immunogen for this GLUT4 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the GLUT4 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
GLUT4 (Glucose Transporter 4) |
| Short name: |
GLUT4 Antibody (Glucose Transporter 4) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GLUT4 (Antibody to) (Glucose Transporter 4) |
| Alternative technique: |
antibodies |
| Identity: |
11009 |
| Gene: |
SLC2A4 |
More about : SLC2A4 |
| Long gene name: |
solute carrier family 2 member 4 |
| Synonyms gene: |
GLUT4 |
| Synonyms gene name: |
member 4 , solute carrier family 2 (facilitated glucose transporter) |
| Locus: |
17p13, 1 |
| Discovery year: |
1989-03-06 |
| GenBank acession: |
M20747 |
| Entrez gene record: |
6517 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000102181 |