| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SERCA2 ATPase |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the SERCA2 ATPase antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This SERCA2 ATPase antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P16615 |
| Purity: |
Antigen affinity |
| Description: |
ATP2B, Expression was also observed in the infundibulum and outer root sheath of hair follicles, In Darier disease skin, Perilesional Darier disease skin was comparable to normal skin, SERCA2 belongs to the large family of P-type cation pumps that couple ATP hydrolysis with cation transport across membranes, SERCA2 was expressed in all specimens, The gene is mapped on 12q24, There was variable suprabasal expression, They are closely related to the plasma membrane Ca(2+)-ATPases, also called ATP2A2, and acantholytic lesional cells, and arrector pili muscle, apocrine gland cells, encodes one of the SERCA Ca(2+)-ATPases, germinative and mature cells of sebaceous glands, or PMCAs, secretory coil and duct of eccrine glands, strong SERCA2 positivity was detected in the basal, suprabasal, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells, with pronounced expression in the subnuclear aspect of basal epidermal keratinocytes, 11, Sarcoplasmic reticulum Ca(2+)-ATPase 2 |
| Immunogen: |
mouse and rat), An amino acid sequence from the middle region of human SERCA2 ATPase (QRDACLNARCFARVE) was used as the immunogen for this SERCA2 ATPase antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SERCA2 ATPase antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SERCA2 ATPase |
| Short name: |
SERCA2 ATPase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SERCA2 ATPase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
812 |
| Gene: |
ATP2A2 |
More about : ATP2A2 |
| Long gene name: |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
| Synonyms gene: |
ATP2B DAR |
| Synonyms gene name: |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| Synonyms: |
SERCA2 |
| Synonyms name: |
sarcoplasmic/endoplasmic reticulum calcium ATPase 2 calcium pump 2 |
| Locus: |
12q24, 11 |
| Discovery year: |
1990-09-10 |
| Entrez gene record: |
488 |
| Pubmed identfication: |
10080178 |
| RefSeq identity: |
NM_001681 |
| Classification: |
ATPases Ca2+ transporting |
| Havana BLAST/BLAT: |
OTTHUMG00000169327 |