| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SERCA1 ATPase |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the SERCA1 ATPase antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This SERCA1 ATPase antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O14983 |
| Purity: |
Antigen affinity |
| Description: |
1 of which can be alternatively spliced, Mutations in this gene cause some autosomal recessive forms of Brody disease, Overexpression of S1T, This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, This gene encodes one of the SERCA Ca(2+)-ATPases, Zhang et al, also called ATP2A1, and is involved in muscular excitation and contraction, but not full-length SERCA1, characterized by increasing impairment of muscular relaxation during exercise, induced ER stress in HeLa cells and amplified ER stress through the PERK(EIF2AK3)-EIF2A -ATF4 -CHOP (DDIT3) pathway, is an enzyme that in humans is encoded by the ATP2A1 gene, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells, (1995) determined that the human ATP2A1 gene is 26 kb long and contains 23 exons, SERCA1 (Sarcoplasmic reticulum Ca(2+)-ATPase 1 |
| Immunogen: |
mouse and rat), An amino acid sequence from the middle region of human SERCA1 ATPase (EQREACRRACCFARVE) was used as the immunogen for this SERCA1 ATPase antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SERCA1 ATPase antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SERCA1 ATPase |
| Short name: |
SERCA1 ATPase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SERCA1 ATPase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
811 |
| Gene: |
ATP2A1 |
More about : ATP2A1 |
| Long gene name: |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 |
| Synonyms gene: |
ATP2A |
| Synonyms gene name: |
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| Synonyms: |
SERCA1 |
| Synonyms name: |
sarcoplasmic/endoplasmic reticulum calcium ATPase 1 calcium pump 1 |
| Locus: |
16p11, 2 |
| Discovery year: |
1990-09-10 |
| Entrez gene record: |
487 |
| RefSeq identity: |
NM_004320 |
| Classification: |
ATPases Ca2+ transporting |
| Havana BLAST/BLAT: |
OTTHUMG00000131760 |