| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TNR |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the TNR antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TNR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q92752 |
| Purity: |
Antigen affinity |
| Description: |
It is a member of the tenascin (TN) gene family, It is an extracellular matrix protein expressed primarily in the central nervous system, It is suggested that Tenascin-R has a role in initiating the detachment of neuroblasts from tangential chains and in initiating radial migration of the cells, TNR has been detected predominantly in the central nervous system and is localized around motor neurons and on motor axons in the spinal cord, TNX (TNXB), The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues, and TNR, and olfactory bulb, cerebellum, hippocampus, which includes at least 3 genes in mammals: TNC (Hexabrachion), Tenascin-R is a protein that in humans is encoded by the TNR gene |
| Immunogen: |
An amino acid sequence from the N-terminus of mouse Tenascin-R (QTSDHESQVTFTHK) was used as the immunogen for this TNR antibody (100% rat homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TNR antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TNR |
| Short name: |
TNR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
tenascin R (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
TN-R, TNR and IDBG-104981 and ENSG00000116147 and 7143, TNR and IDBG-636417 and ENSBTAG00000011706 and 526409, Tnr and IDBG-200901 and ENSMUSG00000015829 and 21960, glutamatergic and biological process this GO :0051971 and positive regulation of transmission of nerve impulse and biological process this GO :0060291 and long-term synaptic potentiation and biological process this GO :0072534 and perineuronal net and cellular component, nuclei, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007158 and neuron cell-cell adhesion and biological process this GO :0007411 and axon guidance and biological process this GO :0008306 and associative learning and biological process this GO :0009986 and cell surface and cellular component this GO :0010977 and negative regulation of neuron projection development and biological process this GO :0022029 and telencephalon cell migration and biological process this GO :0022408 and negative regulation of cell-cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030517 and negative regulation of axon extension and biological process this GO :0035641 and locomotory exploration behavior and biological process this GO :0045121 and membrane raft and cellular component this GO :0048692 and negative regulation of axon extension involved in regeneration and biological process this GO :0050804 and regulation of synaptic transmission and biological process this GO :0050805 and negative regulation of synaptic transmission and biological process this GO :0050808 and synapse organization and biological process this GO :0050885 and neuromuscular process controlling balance and biological process this GO :0051968 and positive regulation of synaptic transmission, this GO :0005515 : protein binding, this GO :0005515 : protein binding, tenascin R |
| Identity: |
11953 |
| Gene: |
TNR |
More about : TNR |
| Long gene name: |
tenascin R |
| Synonyms name: |
restrictin janusin |
| Locus: |
1q25, 1 |
| Discovery year: |
1995-10-24 |
| GenBank acession: |
X98085 |
| Entrez gene record: |
7143 |
| Pubmed identfication: |
8626505 8940128 |
| RefSeq identity: |
NM_003285 |
| Classification: |
Fibronectin type III domain containing Fibrinogen C domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000034876 |