| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PI3K (p85 beta) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the PI3K antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This PI3K antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O00459 |
| Purity: |
Antigen affinity |
| Description: |
Binding of p85-beta and activation of PI3K required tyr89 of NS1, Overexpression of the protein in livers of ob/ob mice increased glucose tolerance and reduced blood glucose concentrations, PIK3R2 and PIK3, Park et al, The NS1 protein from various influenza strains bind p85-beta, Using mouse embryonic fibroblasts, a transcription factor that orchestrates the unfolded protein response (UPR) following endoplasmic reticulum (ER) stress, also called p85-Beta, and mutant viruses expressing NS1 with a tyr89-to-phe substitution grew more slowly in cell culture than wildtype viruses, but not p85-alpha, in addition to regulating PI3K function, is an enzyme that in humans is encoded by the PIK3R2 gene, p85-alpha/beta regulated the function of Xbp1s, showed that, Phosphatidylinositol 3-kinase regulatory subunit 2 |
| Immunogen: |
mouse and rat homology), Amino acids 447-461 (KVYHQQYQDKSREYD-beta specific) was used as the immunogen for this PI3K antibody (100% human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PI3K antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PI3K (p85 beta) |
| Short name: |
PI3K Antibody (p85 beta) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PI3K (Antibody to) (p85 b) |
| Alternative technique: |
antibodies |
| Identity: |
8975 |
| Gene: |
PIK3CA |
More about : PIK3CA |
| Long gene name: |
phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit alpha |
| Synonyms gene name: |
alpha polypeptide phosphatidylinositol-4, catalytic, catalytic subunit alpha , phosphoinositide-3-kinase, 5-bisphosphate 3-kinase |
| Synonyms: |
PI3K |
| Locus: |
3q26, 32 |
| Discovery year: |
1994-07-15 |
| Entrez gene record: |
5290 |
| Pubmed identfication: |
1322797 |
| Classification: |
Phosphatidylinositol 3-kinase subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000157311 |
| Locus Specific Databases: |
LRG_310 |