| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NFAT2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the NFAT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This NFAT2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O95644 |
| Purity: |
Antigen affinity |
| Description: |
And it is also a component of the nuclear factor of activated T cells DNA-binding transcription complex, It is an inducible nuclear component which functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A, NFATC1/NFAT2 was not detected in brain, Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response, The NFATC1 gene is mapped on 18q23, The solution structure of the binary complex formed between the core DNA-binding domain of human NFAT2 and the 12-bp oligonucleotide duplex containing the ARRE2 DNA site from the IL2 promoter, also known as NFATC or NFAT2, cytoplasmic 1, is a protein that in humans is encoded by the NFATC1 gene, liver, or kidney, Nuclear factor of activated T-cells |
| Immunogen: |
An amino acid sequence from the C-terminus of human NFAT2 (AIFLTVSREHERVGCFF) was used as the immunogen for this NFAT2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the NFAT2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NFAT2 |
| Short name: |
NFAT2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NFAT2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7775 |
| Gene: |
NFATC1 |
More about : NFATC1 |
| Long gene name: |
nuclear factor of activated T-cells 1 |
| Synonyms gene name: |
calcineurin-dependent 1 , cytoplasmic, nuclear factor of activated T-cells |
| Synonyms: |
NF-ATC NFATc NFAT2 |
| Locus: |
18q23 |
| Discovery year: |
1994-11-16 |
| GenBank acession: |
U08015 |
| Entrez gene record: |
4772 |
| Pubmed identfication: |
8202141 |
| RefSeq identity: |
NM_172390 |
| Classification: |
Nuclear factors of activated T-cells |
| Havana BLAST/BLAT: |
OTTHUMG00000132897 |