| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Cytoglobin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Cytoglobin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Cytoglobin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q8WWM9 |
| Purity: |
Antigen affinity |
| Description: |
Because the oxygen affinity of CYGB is more similar to myoglobin than to neuroglobin, CYGB is proposed to represent a tissue oxygen reservoir, Cytoglobin has many elements common to vertebrate globins, In contrast to the high oxygen affinities displayed by most hexacoordinate hemoglobins, The CYGB gene contains four exons and spans about 9 kb, also called HGB or STAP, and the amino acids that form the heme pocket share similarity with pentacoordinate myoglobin, and the oxy form of CYGB resists autooxidation, including invariant histidine residues, is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, or serve a protective function during oxidative stress, scavenge nitric oxide or other reactive oxygen species, the characteristics of CYGB indicate that it can facilitate oxygen transport, Cytoglobin (CYGB) |
| Immunogen: |
An amino acid sequence from the N-terminus of human Cytoglobin (FVNFPSAKQYFSQFKHMED) was used as the immunogen for this Cytoglobin antibody (100% rat homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cytoglobin antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Cytoglobin |
| Short name: |
Cytoglobin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cytoglobin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16505 |
| Gene: |
CYGB |
More about : CYGB |
| Long gene name: |
cytoglobin |
| Synonyms: |
HGB STAP |
| Synonyms name: |
stellate cell activation-associated protein histoglobin |
| Locus: |
17q25, 1 |
| Discovery year: |
2001-09-21 |
| GenBank acession: |
AJ315162 |
| Entrez gene record: |
114757 |
| Pubmed identfication: |
11919282 |
| RefSeq identity: |
NM_134268 |
| Havana BLAST/BLAT: |
OTTHUMG00000180289 |