| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Stefin B |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Stefin B antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Stefin B antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q62426 |
| Purity: |
Antigen affinity |
| Description: |
A STFB multiprotein complex might have a specific cerebellar function, It has been isolated from human spleen and liver and its amino acid sequence has been fully determined, It is able to form a dimer stabilized by noncovalent forces, Its role is though to be as a protector against the proteinases leaking from lysosomes, STFB becomes excluded from the nucleus and lysosomes, The gene is located on 21q22, The protein is widely distributed and is localized mostly intracellularly, Upon differentiation to myotubes, also called Stefin B (STFB), and that the loss of this function might contribute to the etiopathogenesis of EPM1, but has been found extracellularly, h and b, inhibiting papain and cathepsins l, is a small protein that is a member of the superfamily of cysteine protease inhibitors, suggesting that the subcellular distribution of the protein is dependent on the differentiation status of the cell, 3, Cystatin B (CSTB) |
| Immunogen: |
An amino acid sequence from the middle region of mouse Stefin B (DKCVHLRVFQPLPHEN) was used as the immunogen for this Stefin B antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Stefin B antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Stefin B |
| Short name: |
Stefin B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Stefin B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3412 |
| Gene: |
EPM1 |
More about : EPM1 |
| Long gene name: |
cystatin B |
| Synonyms gene: |
STFB |
| Synonyms gene name: |
cystatin B (stefin B) |
| Synonyms: |
CST6 PME CSTB |
| Synonyms name: |
stefin B |
| Locus: |
21q22, 3 |
| Discovery year: |
1996-12-12 |
| GenBank acession: |
L03558 |
| Entrez gene record: |
1476 |
| Pubmed identfication: |
8596935 |
| RefSeq identity: |
NM_000100 |
| Classification: |
Cystatins, type 1 |
| Havana BLAST/BLAT: |
OTTHUMG00000086886 |
| Locus Specific Databases: |
LRG_485 |