| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
5HT1A Receptor |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the 5HT1A Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This 5HT1A Receptor antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P08908 |
| Purity: |
Antigen affinity |
| Description: |
Activation of 5HT1ARs has been demonstrated to impair cognition, In the dorsal raphe nucleus they are co-localized with neurokinin 1(NK1) receptors and have been shown to inhibit the release of substance P, It is a G protein-coupled receptor (GPCR) that is coupled to Gi/Go and mediates inhibitory neurotransmission, The HTR1A gene is located at 5q12, The decreases in 5HT1AR densities correlated with decreased glucose utilization as measured by PET scan, and memory by inhibiting the release of glutamate and acetylcholine in various areas of the brain, learning, their endogenous ligand, 3, 5HT1AR is a subtype of 5HTR that binds the endogenous neurotransmitter serotonin |
| Immunogen: |
An amino acid sequence from the C-terminus of human 5HT1A Receptor(NKDFQNAFKKIIKCKFCRQ) was used as the immunogen for this 5HT1A Receptor antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the 5HT1A Receptor antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
5HT1A Receptor |
| Short name: |
5HT1A Receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
5HT1A Receptor (Antibody to) |
| Alternative technique: |
antibodies |