| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Cystathionase |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the Cystathionase antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Cystathionase antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P32929 |
| Purity: |
Antigen affinity |
| Description: |
Cystathionine is physiologically activated by calcium and calmodulin, In some bacteria and mammals, Mutant mice lacking CTH displayed pronounced hypertension and diminished endothelium-dependent vasorelaxation, and other tissues, aorta, heart, including humans, this enzyme takes part in generating hydrogen sulfide and that genetic deletion of this enzyme in mice markedly reduced H2S levels in the serum, which is a mechanism for H2S formation in response to vascular activation, Cystathionine gamma lyase (from the CTH gene) is an enzyme which breaks down cystathionine into cysteine and alpha-ketobutyrate |
| Immunogen: |
An amino acid sequence from the middle region of human Cystathionase (DVYGGTNRYFRQVASEFGLK) was used as the immunogen for this Cystathionase antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cystathionase antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Cystathionase |
| Short name: |
Cystathionase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cystathionase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2501 |
| Gene: |
CTH |
More about : CTH |
| Long gene name: |
cystathionine gamma-lyase |
| Synonyms gene name: |
cystathionase (cystathionine gamma-lyase) |
| Locus: |
1p31, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
BC015807 |
| Entrez gene record: |
1491 |
| Pubmed identfication: |
1339280 |
| RefSeq identity: |
NM_001902 |
| Havana BLAST/BLAT: |
OTTHUMG00000009352 |