| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Integrin beta 3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Integrin beta 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Integrin beta 3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P05106 |
| Purity: |
Antigen affinity |
| Description: |
Although the protein is expressed on the cell surface at normal levels and is capable of function following extracellular stimulation, CD61, GPIIIa, It is a cluster of differentiation found on thrombocytes, The ITGB3 complex belongs to the integrin class of cell adhesion molecule receptors that share a common heterodimeric structure with alpha and beta subunits, The ITGB3 complex mediates platelet aggregation by acting as a receptor for fibrinogen, also called GP3A, is a protein that in humans is encoded by the ITGB3 gene, it could not be activated via the inside-out signaling pathways, ITGB3 (Integrin beta 3) |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human Integrin beta 3 (EFAKFEEERARAKWDTANN) was used as the immunogen for this Integrin beta 3 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Integrin beta 3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Integrin beta 3 |
| Short name: |
Integrin beta 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Integrin b 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6157 |
| Gene: |
ITGB3BP |
More about : ITGB3BP |
| Long gene name: |
integrin subunit beta 3 binding protein |
| Synonyms gene name: |
integrin beta 3 binding protein (beta3-endonexin) |
| Synonyms: |
NRIF3 HSU37139 TAP20 CENPR |
| Synonyms name: |
centromere protein R beta3-endonexin |
| Locus: |
1p31, 3 |
| Discovery year: |
2000-05-08 |
| GenBank acession: |
U37139 |
| Entrez gene record: |
23421 |
| Pubmed identfication: |
7593198 10490654 |
| RefSeq identity: |
NM_014288 |
| Havana BLAST/BLAT: |
OTTHUMG00000013364 |