| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IL5RA |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the IL5RA antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This IL5RA antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q01344 |
| Purity: |
Antigen affinity |
| Description: |
And its cytogenetic location is 3p26, The IL5RA gene is mapped to 3p26-p24 by Southern blot analysis of DNA from a panel of mouse-human hybrid somatic cell lines complemented by in situ hybridization, The binding of this protein to IL5 depends on the beta subunit which is activated by the ligand binding and is required for the biological activities of IL5, The protein encoded by the IL5RA gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), Within a 15-residue stretch of IL5RA, also known as CD125, and interleukin 5(IL5), colony stimulating factor 2(CSF2/GM-CSF), is a subunit of the Interleukin-5 receptor, the C-terminal phenylalanine is critical, 2, Interleukin 5 receptor alpha |
| Immunogen: |
An amino acid sequence from the N-terminus of human IL5RA (NPDQEQRNVNLEYQVK) was used as the immunogen for this IL5RA antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IL5RA antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IL5RA |
| Short name: |
IL5RA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
alpha (Antibody to), interleukin 5 receptor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD125 and CDw125 and HSIL5R3 and IL5R, Extracellular, IL5RA and IDBG-13590 and ENSG00000091181 and 3568, IL5RA and IDBG-644842 and ENSBTAG00000000273 and 615848, Il5ra and IDBG-173890 and ENSMUSG00000005364 and 16192, alpha, protein binding, this GO :0002437 and inflammatory response to antigenic stimulus and biological process this GO :0004896 and cytokine receptor activity and molecular function this GO :0004914 and interleukin-5 receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032674 and regulation of interleukin-5 production and biological process this GO :0038043 and interleukin-5-mediated signaling pathway and biological process this GO :0071310 and cellular response to organic substance and biological process, this GO :0004896 : cytokine receptor activity, this GO :0004896 : cytokine receptor activity and also this GO :0004914 : interleukin-5 receptor activity and also this GO :0005515 : protein binding, this GO :0004914 : interleukin-5 receptor activity, this GO :0005515 : protein binding, interleukin 5 receptor |
| Identity: |
6017 |
| Gene: |
IL5RA |
More about : IL5RA |
| Long gene name: |
interleukin 5 receptor subunit alpha |
| Synonyms gene: |
IL5R |
| Synonyms gene name: |
alpha , interleukin 5 receptor |
| Synonyms: |
CDw125 CD125 |
| Locus: |
3p26, 2 |
| Discovery year: |
1992-06-18 |
| GenBank acession: |
M96652 |
| Entrez gene record: |
3568 |
| Pubmed identfication: |
1732409 |
| Classification: |
CD molecules Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000090245 |