| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
LAMC2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the LAMC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This LAMC2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13753 |
| Purity: |
Antigen affinity |
| Description: |
IV and III are shorter, It is expressed in several fetal tissues but differently from gamma1, Laminins, The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, The gamma2 chain, They have been implicated in a wide variety of biological processes including cell adhesion, This gene encodes the gamma chain isoform laminin, a family of extracellular matrix glycoproteins, a skin disease characterized, and domains V, and is specifically localized to epithelial cells in skin, and mutations in this gene have been associated with junctional epidermolysis bullosa, are the major noncollagenous constituent of basement membranes, differentiation, formerly though to be a truncated version of beta chain(B2t), gamma2, however, is highly homologous to the gamma1 chain, it lacks domain VI, lung and kidney, migration, neurite outgrowth and metastasis, signaling, Laminin subunit gamma-2 is a protein that in humans is encoded by the LAMC2 gene |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of LAMC2 (ETSIDGILADVKNLENIRDNL) was used as the immunogen for this LAMC2 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the LAMC2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
LAMC2 |
| Short name: |
LAMC2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
gamma 2 (Antibody to), laminin |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
B2T and BM600 and CSF and EBR2 and EBR2A and LAMB2T and LAMNB2, Extracellular, LAMC2 and IDBG-105293 and ENSG00000058085 and 3918, LAMC2 and IDBG-637198 and ENSBTAG00000000793 and 511043, Lamc2 and IDBG-198823 and ENSMUSG00000026479 and 16782, gamma 2, heparin binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005604 and basement membrane and cellular component this GO :0005607 and laminin-2 complex and cellular component this GO :0005610 and laminin-5 complex and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005938 and cell cortex and cellular component this GO :0007155 and cell adhesion and biological process this GO :0008201 and heparin binding and molecular function this GO :0008544 and epidermis development and biological process this GO :0016020 and membrane and cellular component this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0031581 and hemidesmosome assembly and biological process this GO :0034329 and cell junction assembly and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008201 : heparin binding, this GO :0008201 : heparin binding, laminin |
| Identity: |
6493 |
| Gene: |
LAMC2 |
More about : LAMC2 |
| Long gene name: |
laminin subunit gamma 2 |
| Synonyms gene: |
EBR2 LAMB2T LAMNB2 EBR2A |
| Synonyms gene name: |
BM600 (100kD), Herlitz junctional epidermolysis bullosa)) laminin, gamma 2 , gamma 2 (nicein (100kD), kalinin (105kD), laminin |
| Synonyms: |
nicein-100kDa kalinin-105kDa BM600-100kDa |
| Locus: |
1q25, 3 |
| Discovery year: |
1993-07-13 |
| GenBank acession: |
Z15008 |
| Entrez gene record: |
3918 |
| Pubmed identfication: |
1383240 |
| RefSeq identity: |
NM_005562 |
| Classification: |
Laminin subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000035520 |