| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Bcl3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Bcl3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This Bcl3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P20749 |
| Purity: |
Antigen affinity |
| Description: |
It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia, The BCL3 gene is mapped to human chromosome 19, The expression of this gene can be induced by NF-kappa B, The protein encoded by this gene contains seven ankyrin repeats, This gene is a proto-oncogene candidate, This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers, which are most closely related to those found in I kappa B proteins, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B, B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene |
| Immunogen: |
An amino acid sequence from the middle region of human Bcl3 (MALDRHGQTAAHLACEHR) was used as the immunogen for this Bcl3 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Bcl3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Bcl3 |
| Short name: |
Bcl3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
B-cell CLL/lymphoma 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
998 |
| Gene: |
BCL3 |
More about : BCL3 |
| Long gene name: |
B-cell CLL/lymphoma 3 |
| Synonyms gene: |
D19S37 BCL4 |
| Synonyms name: |
B-cell lymphoma 3-encoded protein B-cell leukemia/lymphoma 3 chronic lymphatic leukemia protein |
| Locus: |
19q13, 32 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M31732 |
| Entrez gene record: |
602 |
| Pubmed identfication: |
1501714 2180580 |
| RefSeq identity: |
NM_005178 |
| Classification: |
Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000151517 |